| Issue |
ITM Web Conf.
Volume 26, 2019
2018 International Conference on Computer Science and Education Technology (CSET 2018)
|
|
|---|---|---|
| Article Number | 02004 | |
| Number of page(s) | 4 | |
| Section | Information Science and Biomedical Science | |
| DOI | https://doi.org/10.1051/itmconf/20192602004 | |
| Published online | 04 February 2019 | |
Experimental Verification of Gene Expression Related to Lung Cancer in Nasal Epitthelia
Zhongshan Hospital of Xiamen University, 209 South Hubin Rd., Xiamen, 361004, China
a Corresponding author: xmdsy@xmu.edu.cn
Genes expression related to lung cancer are observed in nasal epitthelia, to identify their similarities and differences and provide the basis for possible application. There are three groups:non-lung cancer group (NLC), lung cancer group (LC) and postoperative lung cancer group (PLC).The genes expression in nasal epitthelia were observed by PCR, including the HCK, NCF1, TLR8, EMR3, CSF2RB, DYSF, SPEF2, ANKFN1, HYDIN, DNAH5, C12orf55 and CCDC113. Their expression levels were obtained and statistically compared. Results showed that all the related genes in LC and PLC groups were highly expressed. There are significant difference in HCK, NCF1, TLR8, EMR3, CSF2RB and C12orf55 gene expression between the LC or PLC and NLC, and in EMR3 and C12orf55 between LC and PLC. Conclusions are HCK, NCF1, TLR8, EMR3, CSF2RB, C12orf55 can be used for lung cancer screening, while EMR3 and C12orf55 for the review of post-operative lung cancer.
© The Authors, published by EDP Sciences, 2019
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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