| Issue |
ITM Web of Conferences
Volume 5, 2015
Workshop on Multiscale and Hybrid Modelling in Cell and Cell Population Biology
|
|
|---|---|---|
| Article Number | 00012 | |
| Number of page(s) | 4 | |
| DOI | https://doi.org/10.1051/itmconf/20150500012 | |
| Published online | 11 December 2015 | |
Hybrid modelling of mechanical cues in cell migration
1 Université Grenoble Alpes, CNRS, TIMC-IMAG / DyCTiM, 38000 Grenoble, France
2 Université de Montpellier II, CNRS, LMGC, UMR 5508, 34095 Montpellier cedex 5, France
a e-mail: angelique.stephanou@imag.fr
Many studies stress the crucial importance of the mechanical component in angiogenesis, but still very few models really integrate mechanics. We propose to investigate the importance of mechanical cues for cell migration in this context with a new hybrid continuous-discrete model that describes the individual migration of contracting cells on an elastic matrix of fibres. The matrix is described as a continuum substrate whereas the cells are described as discrete elements.
© Owned by the authors, published by EDP Sciences, 2015
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